To Mask or Not to Mask to Avoid Getting COVID-19 | by Nancy R ...COVID-19, the disease caused by the novel coronavirus, brings with it a host of health concerns. Most of these symptoms are respiratory in nature as reported by the CDC; shortness of breath, coughing, sore throat [1]. However, there is some concern that the coronavirus may cause some neurological symptoms as well.

In a study of 214 patients with varying degrees of respiratory involvement from novel coronavirus, 36.4% of patients had symptoms of neurologic manifestations that involved central nervous system, peripheral nervous system, and skeletal muscles [2]. There is also some initial evidence that the virus may cause damage to the hearing organs of the inner ear.

Currently, there is little evidence published connecting novel coronavirus and tinnitus directly. But according to the American Tinnitus Association, pre-existing behavioral conditions may make it more likely patients will experience tinnitus due to the stress and depression associated with social isolation and infection avoidance.

For example, one large population study posits that people with generalized anxiety disorder are nearly seven times more likely to experience chronic, burdensome tinnitus [3].  As we continue to isolate ourselves in order to minimize the spread of COVID-19, stress and depression are common emotions we all may experience.

Could a vaccine harm the auditory system?

ONLINE FEATURE | Ototoxicity of FDA-Approved Drugs Being Re ...While it is too early to know whether a potential vaccine will have any risk of ototoxicity (meaning “poisonous to the ear”), some currently discussed treatments do pose a potential risk to the auditory system.

The quinine family of drugs, historically used for prophylactic prevention and treatment of malaria, have some history of ototoxicity. However, the most recent trial of this family in treatment of COVID-19 has focused around hydroxychloroquine, which has a lower risk of ototoxicity [4].

A promising therapeutic antiviral being developed and in clinical trials for COVID-19, Remdesivir, does not currently list ototoxicity as a potential side effect, per its maker, Gilead Sciences, Inc.

Enacting safety protocols to minimize the spread of COVID-19

Today, the greatest concern regarding COVID-19 is in transmission. Hearing loss treatment — like most essential health services — include procedures that make social distancing a challenge but are not impossible to execute safely. Telehealth, the proper use of personal protective equipment, curbside service, and appropriate in-office protocols are being put in place that significantly limit exposure potential for both the patient and clinician.

  1. Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China
  2. Seçkin U, Ozoran K, Ikinciogullari A, Borman P, Bostan EE. Hydroxychloroquine ototoxicity in a patient with rheumatoid arthritis. Rheumatol Int. 2000;19:203–204.